Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity

Innate immune signaling via TLR4 plays critical roles in pathogenesis of metabolic disorders, but the contribution of different lipid species to metabolic disorders and inflammatory diseases is less clear. GM3 ganglioside in human serum is composed of a variety of fatty acids, including long‐chain (...

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Publicado no:EMBO J
Main Authors: Kanoh, Hirotaka, Nitta, Takahiro, Go, Shinji, Inamori, Kei‐ichiro, Veillon, Lucas, Nihei, Wataru, Fujii, Mayu, Kabayama, Kazuya, Shimoyama, Atsushi, Fukase, Koichi, Ohto, Umeharu, Shimizu, Toshiyuki, Watanabe, Taku, Shindo, Hiroki, Aoki, Sorama, Sato, Kenichi, Nagasaki, Mika, Yatomi, Yutaka, Komura, Naoko, Ando, Hiromune, Ishida, Hideharu, Kiso, Makoto, Natori, Yoshihiro, Yoshimura, Yuichi, Zonca, Asia, Cattaneo, Anna, Letizia, Marilena, Ciampa, Maria, Mauri, Laura, Prinetti, Alessandro, Sonnino, Sandro, Suzuki, Akemi, Inokuchi, Jin‐ichi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7298289/
https://ncbi.nlm.nih.gov/pubmed/32378734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019101732
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