Modulation of membrane properties of lung cancer cells by azurin enhances the sensitivity to EGFR-targeted therapy and decreased β1 integrin-mediated adhesion

In lung cancer, the Epidermal Growth Factor Receptor (EGFR) is one of the main targets for clinical management of this disease. The effectiveness of therapies toward this receptor has already been linked to the expression of integrin receptor subunit β(1) in NSCLC A549 cells. In this work we demonst...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Bernardes, Nuno, Abreu, Sofia, Carvalho, Filomena A., Fernandes, Fábio, Santos, Nuno C., Fialho, Arsénio M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934055/
https://ncbi.nlm.nih.gov/pubmed/27096894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1172147
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