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The histone chaperone ASF1 regulates the activation of ATM and DNA-PKcs in response to DNA double-strand breaks
The Ataxia-telangiectasia mutated (ATM) kinase and the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) are activated by DNA double-strand breaks (DSBs). These DSBs occur in the context of chromatin but how chromatin influences the activation of these kinases is not known. Here we show that...
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| Udgivet i: | Cell Cycle |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6132960/ https://ncbi.nlm.nih.gov/pubmed/29954236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1486165 |
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