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Interaction of Peptide Aptamers with Prion Protein Central Domain Promotes α-Cleavage of PrP(C)

Prion diseases are infectious and fatal neurodegenerative diseases affecting humans and animals. Transmission is possible within and between species with zoonotic potential. Currently, no prophylaxis or treatment exists. Prions are composed of the misfolded isoform PrP(Sc) of the cellular prion prot...

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Detaylı Bibliyografya
Yayımlandı:Mol Neurobiol
Asıl Yazarlar: Corda, Erica, Du, Xiaotang, Shim, Su Yeon, Klein, Antonia N., Siltberg-Liberles, Jessica, Gilch, Sabine
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132731/
https://ncbi.nlm.nih.gov/pubmed/29460268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-0944-9
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