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Interaction of Peptide Aptamers with Prion Protein Central Domain Promotes α-Cleavage of PrP(C)
Prion diseases are infectious and fatal neurodegenerative diseases affecting humans and animals. Transmission is possible within and between species with zoonotic potential. Currently, no prophylaxis or treatment exists. Prions are composed of the misfolded isoform PrP(Sc) of the cellular prion prot...
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| Udgivet i: | Mol Neurobiol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer US
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6132731/ https://ncbi.nlm.nih.gov/pubmed/29460268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-0944-9 |
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