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Spatial and temporal coordination of insulin granule exocytosis in intact human pancreatic islets

AIMS/HYPOTHESIS: Insulin secretion is widely studied because it plays a central role in glucose homeostasis and diabetes. Processes from insulin granule fusion in beta cells to in vivo insulin secretion have been elucidated, but data at the cellular level do not fully account for several aspects of...

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Dettagli Bibliografici
Pubblicato in:Diabetologia
Autori principali: Almaça, Joana, Liang, Tao, Gaisano, Herbert Y., Nam, Hong Gil, Berggren, Per-Olof, Caicedo, Alejandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132229/
https://ncbi.nlm.nih.gov/pubmed/26376795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3747-9
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