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Insulin granule biogenesis and exocytosis

Insulin is produced by pancreatic β-cells, and once released to the blood, the hormone stimulates glucose uptake and suppresses glucose production. Defects in both the availability and action of insulin lead to elevated plasma glucose levels and are major hallmarks of type-2 diabetes. Insulin is sto...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Mol Life Sci
Prif Awduron: Omar-Hmeadi, Muhmmad, Idevall-Hagren, Olof
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer International Publishing 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966131/
https://ncbi.nlm.nih.gov/pubmed/33146746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03688-4
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