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Insulin granule biogenesis and exocytosis

Insulin is produced by pancreatic β-cells, and once released to the blood, the hormone stimulates glucose uptake and suppresses glucose production. Defects in both the availability and action of insulin lead to elevated plasma glucose levels and are major hallmarks of type-2 diabetes. Insulin is sto...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Omar-Hmeadi, Muhmmad, Idevall-Hagren, Olof
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966131/
https://ncbi.nlm.nih.gov/pubmed/33146746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03688-4
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