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BIG3 inhibits insulin granule biogenesis and insulin secretion
While molecular regulation of insulin granule exocytosis is relatively well understood, insulin granule biogenesis and maturation and its influence on glucose homeostasis are relatively unclear. Here, we identify a novel protein highly expressed in insulin-secreting cells and name it BIG3 due to its...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197882/ https://ncbi.nlm.nih.gov/pubmed/24711543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201338181 |
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