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Increased biogenesis of glucagon-containing secretory granules and glucagon secretion in BIG3-knockout mice

OBJECTIVE: Although both insulin and glucagon are intimately involved in the regulation of glucose homeostasis, the intrinsic control of glucagon secretion, including the biogenesis and exocytosis of glucagon-containing granules, is far less understood compared with that of insulin. As Brefeldin A-i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Metab
Hauptverfasser: Li, Hongyu, Liu, Tao, Lim, Joy, Gounko, Natalia V., Hong, Wanjin, Han, Weiping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338310/
https://ncbi.nlm.nih.gov/pubmed/25737957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.01.001
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