Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells

Synaptotagmin (Syt)-7, a major component of the exocytotic machinery in neurons, is also the major Syt in rodent pancreatic β-cells shown to mediate glucose-stimulated insulin secretion (GSIS). However, Syt-7’s precise exocytotic actions in β-cells remain unknown. We show that Syt-7 is abundant in h...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Diabetes
Main Authors: Dolai, Subhankar, Xie, Li, Zhu, Dan, Liang, Tao, Qin, Tairan, Xie, Huanli, Kang, Youhou, Chapman, Edwin R., Gaisano, Herbert Y.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2016
Fag:
Islet Studies
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384637/
https://ncbi.nlm.nih.gov/pubmed/27207520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1436
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker