Spatial and temporal coordination of insulin granule exocytosis in intact human pancreatic islets

AIMS/HYPOTHESIS: Insulin secretion is widely studied because it plays a central role in glucose homeostasis and diabetes. Processes from insulin granule fusion in beta cells to in vivo insulin secretion have been elucidated, but data at the cellular level do not fully account for several aspects of...

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Bibliographic Details
Published in:Diabetologia
Main Authors: Almaça, Joana, Liang, Tao, Gaisano, Herbert Y., Nam, Hong Gil, Berggren, Per-Olof, Caicedo, Alejandro
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132229/
https://ncbi.nlm.nih.gov/pubmed/26376795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3747-9
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