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Spatial and temporal coordination of insulin granule exocytosis in intact human pancreatic islets

AIMS/HYPOTHESIS: Insulin secretion is widely studied because it plays a central role in glucose homeostasis and diabetes. Processes from insulin granule fusion in beta cells to in vivo insulin secretion have been elucidated, but data at the cellular level do not fully account for several aspects of...

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Bibliografische gegevens
Gepubliceerd in:Diabetologia
Hoofdauteurs: Almaça, Joana, Liang, Tao, Gaisano, Herbert Y., Nam, Hong Gil, Berggren, Per-Olof, Caicedo, Alejandro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132229/
https://ncbi.nlm.nih.gov/pubmed/26376795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3747-9
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