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Population Pharmacokinetic Modelling of Ceftazidime and Avibactam in the Plasma and Epithelial Lining Fluid of Healthy Volunteers

OBJECTIVES: Our objective was to develop population pharmacokinetic (PK) models for ceftazidime and avibactam in the plasma and epithelial lining fluid (ELF) of healthy volunteers and to compare ELF concentrations to plasma PK/pharmacodynamic (PD) targets. METHODS: Plasma and ELF population PK model...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Drugs R D
Egile Nagusiak: Dimelow, Richard, Wright, James G., MacPherson, Merran, Newell, Paul, Das, Shampa
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer International Publishing 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131119/
https://ncbi.nlm.nih.gov/pubmed/30054895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-018-0241-0
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