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Population Pharmacokinetic Modelling of Ceftazidime and Avibactam in the Plasma and Epithelial Lining Fluid of Healthy Volunteers

OBJECTIVES: Our objective was to develop population pharmacokinetic (PK) models for ceftazidime and avibactam in the plasma and epithelial lining fluid (ELF) of healthy volunteers and to compare ELF concentrations to plasma PK/pharmacodynamic (PD) targets. METHODS: Plasma and ELF population PK model...

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Detaylı Bibliyografya
Yayımlandı:Drugs R D
Asıl Yazarlar: Dimelow, Richard, Wright, James G., MacPherson, Merran, Newell, Paul, Das, Shampa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer International Publishing 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131119/
https://ncbi.nlm.nih.gov/pubmed/30054895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-018-0241-0
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