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Population Pharmacokinetic Modelling of Ceftazidime and Avibactam in the Plasma and Epithelial Lining Fluid of Healthy Volunteers

OBJECTIVES: Our objective was to develop population pharmacokinetic (PK) models for ceftazidime and avibactam in the plasma and epithelial lining fluid (ELF) of healthy volunteers and to compare ELF concentrations to plasma PK/pharmacodynamic (PD) targets. METHODS: Plasma and ELF population PK model...

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Bibliografische gegevens
Gepubliceerd in:Drugs R D
Hoofdauteurs: Dimelow, Richard, Wright, James G., MacPherson, Merran, Newell, Paul, Das, Shampa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131119/
https://ncbi.nlm.nih.gov/pubmed/30054895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-018-0241-0
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