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Ceftazidime‐Avibactam Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Across Adult Indications and Patient Subgroups

Ceftazidime‐avibactam is a novel β‐lactam/β‐lactamase inhibitor combination for the treatment of serious infections caused by resistant gram‐negative pathogens. Population pharmacokinetic (PopPK) models were built to incorporate pharmacokinetic (PK) data from five phase III trials in patients with c...

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Vydáno v:Clin Transl Sci
Hlavní autoři: Li, Jianguo, Lovern, Mark, Green, Michelle L., Chiu, Joannellyn, Zhou, Diansong, Comisar, Craig, Xiong, Yuan, Hing, Jeremy, MacPherson, Merran, Wright, James G., Riccobene, Todd, Carrothers, Timothy J., Das, Shampa
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440567/
https://ncbi.nlm.nih.gov/pubmed/30221827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12585
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