Ceftazidime‐Avibactam Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Across Adult Indications and Patient Subgroups

Ceftazidime‐avibactam is a novel β‐lactam/β‐lactamase inhibitor combination for the treatment of serious infections caused by resistant gram‐negative pathogens. Population pharmacokinetic (PopPK) models were built to incorporate pharmacokinetic (PK) data from five phase III trials in patients with c...

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Bibliografske podrobnosti
izdano v:Clin Transl Sci
Main Authors: Li, Jianguo, Lovern, Mark, Green, Michelle L., Chiu, Joannellyn, Zhou, Diansong, Comisar, Craig, Xiong, Yuan, Hing, Jeremy, MacPherson, Merran, Wright, James G., Riccobene, Todd, Carrothers, Timothy J., Das, Shampa
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440567/
https://ncbi.nlm.nih.gov/pubmed/30221827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12585
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