Ceftazidime‐Avibactam Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Across Adult Indications and Patient Subgroups

Ceftazidime‐avibactam is a novel β‐lactam/β‐lactamase inhibitor combination for the treatment of serious infections caused by resistant gram‐negative pathogens. Population pharmacokinetic (PopPK) models were built to incorporate pharmacokinetic (PK) data from five phase III trials in patients with c...

Full description

Saved in:
Bibliographic Details
Published in:Clin Transl Sci
Main Authors: Li, Jianguo, Lovern, Mark, Green, Michelle L., Chiu, Joannellyn, Zhou, Diansong, Comisar, Craig, Xiong, Yuan, Hing, Jeremy, MacPherson, Merran, Wright, James G., Riccobene, Todd, Carrothers, Timothy J., Das, Shampa
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440567/
https://ncbi.nlm.nih.gov/pubmed/30221827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12585
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items