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PAM forms an atypical SCF ubiquitin ligase complex that ubiquitinates and degrades NMNAT2
PHR (PAM/Highwire/RPM-1) proteins are conserved RING E3 ubiquitin ligases that function in developmental processes, such as axon termination and synapse formation, as well as axon degeneration. At present, our understanding of how PHR proteins form ubiquitin ligase complexes remains incomplete. Alth...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6130950/ https://ncbi.nlm.nih.gov/pubmed/29997255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002176 |
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