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PAM forms an atypical SCF ubiquitin ligase complex that ubiquitinates and degrades NMNAT2

PHR (PAM/Highwire/RPM-1) proteins are conserved RING E3 ubiquitin ligases that function in developmental processes, such as axon termination and synapse formation, as well as axon degeneration. At present, our understanding of how PHR proteins form ubiquitin ligase complexes remains incomplete. Alth...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Desbois, Muriel, Crawley, Oliver, Evans, Paul R., Baker, Scott T., Masuho, Ikuo, Yasuda, Ryohei, Grill, Brock
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130950/
https://ncbi.nlm.nih.gov/pubmed/29997255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002176
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