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Autophagy is inhibited by ubiquitin ligase activity in the nervous system

Autophagy is an intracellular catabolic process prominent in starvation, aging and disease. Neuronal autophagy is particularly important, as it affects the development and function of the nervous system, and is heavily implicated in neurodegenerative disease. Nonetheless, how autophagy is regulated...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Crawley, Oliver, Opperman, Karla J., Desbois, Muriel, Adrados, Isabel, Borgen, Melissa A., Giles, Andrew C., Duckett, Derek R., Grill, Brock
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825199/
https://ncbi.nlm.nih.gov/pubmed/31676756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12804-3
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