Autophagy is inhibited by ubiquitin ligase activity in the nervous system

Autophagy is an intracellular catabolic process prominent in starvation, aging and disease. Neuronal autophagy is particularly important, as it affects the development and function of the nervous system, and is heavily implicated in neurodegenerative disease. Nonetheless, how autophagy is regulated...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Crawley, Oliver, Opperman, Karla J., Desbois, Muriel, Adrados, Isabel, Borgen, Melissa A., Giles, Andrew C., Duckett, Derek R., Grill, Brock
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825199/
https://ncbi.nlm.nih.gov/pubmed/31676756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12804-3
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