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An atypical SCF-like ubiquitin ligase complex promotes Wallerian degeneration through regulation of axonal Nmnat2
Axon degeneration is a tightly regulated self-destructive program that is a critical feature of many neurodegenerative diseases, but the molecular mechanisms regulating this program remain poorly understood. Here we identify Skp1a, a core component of an SCF-type E3 ubiquitin ligase complex, as a cr...
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| Publicado no: | Cell Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5075525/ https://ncbi.nlm.nih.gov/pubmed/27732853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.043 |
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