Lupus acceleration by a MAVS-activating RNA virus requires endosomal TLR signaling and host genetic predisposition

Viruses have long been implicated in the pathogenesis of autoimmunity, yet their contribution remains circumstantial partly due to the lack of well-documented information on infections prior to autoimmune disease onset. Here, we used the lymphocytic choriomeningitis virus (LCMV) as a model to mechan...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Gonzalez-Quintial, Rosana, Nguyen, Anthony, Kono, Dwight H., Oldstone, Michael B. A., Theofilopoulos, Argyrios N., Baccala, Roberto
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130858/
https://ncbi.nlm.nih.gov/pubmed/30199535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203118
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