A carregar...

Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus

Using the Unc93b1 3d mutation that selectively abolishes nucleic acid-binding Toll-like receptor (TLR) (TLR3, -7, -9) signaling, we show these endosomal TLRs are required for optimal production of IgG autoAbs, IgM rheumatoid factor, and other clinical parameters of disease in 2 lupus strains, B6-Fas...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kono, Dwight H., Haraldsson, M. Katarina, Lawson, Brian R., Pollard, K. Michael, Koh, Yi Ting, Du, Xin, Arnold, Carrie N., Baccala, Roberto, Silverman, Gregg J., Beutler, Bruce A., Theofilopoulos, Argyrios N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715524/
https://ncbi.nlm.nih.gov/pubmed/19574451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905441106
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!