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Anti-IFNAR Antibody Treatment Ameliorates Disease in Lupus-Predisposed Mice
The demonstration in humans and mice that nucleic acid-sensing Toll-like receptors (TLRs) and type I interferons (IFNs) are essential disease mediators is a milestone in delineating the mechanisms of lupus pathogenesis. Here, we show that Ifnb gene deletion does not modify disease progression in NZB...
में बचाया:
| मुख्य लेखकों: | , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530925/ https://ncbi.nlm.nih.gov/pubmed/23175700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201477 |
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