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An agonist antibody that blocks autoimmunity by inducing anti-inflammatory macrophages

We have devised a method of using intracellular combinatorial libraries to select antibodies that control cell fates. Many agonist antibodies have been selected with this method, and the process appears to be limited only by the availability of a phenotypic selection system. We demonstrate the utili...

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Vydáno v:FASEB J
Hlavní autoři: Han, Kyung Ho, Gonzalez-Quintial, Rosana, Peng, Yingjie, Baccala, Roberto, Theofilopoulos, Argyrios N., Lerner, Richard A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188224/
https://ncbi.nlm.nih.gov/pubmed/26481307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-281329
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