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Strategies to address chimeric antigen receptor tonic signalling
Adoptive cell transfer using chimeric antigen receptors (CARs) has emerged as one of the most promising new therapeutic modalities for patients with relapsed or refractory B-cell malignancies. Thus far, results in patients with advanced solid tumours have proven disappointing. Constitutive tonic sig...
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| Udgivet i: | Mol Cancer Ther |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6130819/ https://ncbi.nlm.nih.gov/pubmed/30181329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-1097 |
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