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Tumor microenvironment in focus: LA-ICP-MS bioimaging of a preclinical tumor model upon treatment with platinum(iv)-based anticancer agents†

The selection of drug candidates for entering clinical development relies on in vivo testing in (solid) tumor animal models. However, the heterogeneity of tumor tissue (e.g. in terms of drug uptake or tissue composition) is rarely considered when testing novel drug candidates. Therefore, we used the...

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書誌詳細
出版年:Metallomics
主要な著者: Theiner, Sarah, Kornauth, Christoph, Varbanov, Hristo P., Galanski, Markus, Van Schoonhoven, Sushilla, Heffeter, Petra, Berger, Walter, Egger, Alexander E., Keppler, Bernhard K.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130778/
https://ncbi.nlm.nih.gov/pubmed/25856224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5mt00028a
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