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FastSKAT: Sequence kernel association tests for very large sets of markers

The Sequence Kernel Association Test (SKAT) is widely used to test for associations between a phenotype and a set of genetic variants, that are usually rare. Evaluating tail probabilities or quantiles of the null distribution for SKAT requires computing the eigenvalues of a matrix related to the gen...

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Détails bibliographiques
Publié dans:Genet Epidemiol
Auteurs principaux: Lumley, Thomas, Brody, Jennifer, Peloso, Gina, Morrison, Alanna, Rice, Kenneth
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129408/
https://ncbi.nlm.nih.gov/pubmed/29932245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22136
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