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FastSKAT: Sequence kernel association tests for very large sets of markers

The Sequence Kernel Association Test (SKAT) is widely used to test for associations between a phenotype and a set of genetic variants, that are usually rare. Evaluating tail probabilities or quantiles of the null distribution for SKAT requires computing the eigenvalues of a matrix related to the gen...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Lumley, Thomas, Brody, Jennifer, Peloso, Gina, Morrison, Alanna, Rice, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129408/
https://ncbi.nlm.nih.gov/pubmed/29932245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22136
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