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Rare variant testing across methods and thresholds using the multi-kernel sequence kernel association test (MK-SKAT)
Analysis of rare genetic variants has focused on region-based analysis wherein a subset of the variants within a genomic region is tested for association with a complex trait. Two important practical challenges have emerged. First, it is difficult to choose which test to use. Second, it is unclear w...
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| Published in: | Stat Interface |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4698916/ https://ncbi.nlm.nih.gov/pubmed/26740853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4310/SII.2015.v8.n4.a8 |
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