Rare variant testing across methods and thresholds using the multi-kernel sequence kernel association test (MK-SKAT)

Analysis of rare genetic variants has focused on region-based analysis wherein a subset of the variants within a genomic region is tested for association with a complex trait. Two important practical challenges have emerged. First, it is difficult to choose which test to use. Second, it is unclear w...

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Bibliographic Details
Published in:Stat Interface
Main Authors: Urrutia, Eugene, Lee, Seunggeun, Maity, Arnab, Zhao, Ni, Shen, Judong, Li, Yun, Wu, Michael C.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698916/
https://ncbi.nlm.nih.gov/pubmed/26740853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4310/SII.2015.v8.n4.a8
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