Marked disparity of microRNA modulation by cGMP-selective PDE5 versus PDE9 inhibitors in heart disease

MicroRNAs (miRs) posttranscriptionally regulate mRNA and its translation into protein, and are considered master controllers of genes modulating normal physiology and disease. There is growing interest in how miRs change with drug treatment, and leveraging this for precision guided therapy. Here we...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: Kokkonen-Simon, Kristen M., Saberi, Amir, Nakamura, Taishi, Ranek, Mark J., Zhu, Guangshuo, Bedja, Djahida, Kuhn, Michaela, Halushka, Marc K., Lee, Dong Ik, Kass, David A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2018
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129132/
https://ncbi.nlm.nih.gov/pubmed/30089721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121739
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