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Direct activation of PDE5 by cGMP: long-term effects within NO/cGMP signaling
In platelets, the nitric oxide (NO)–induced cGMP response is indicative of a highly regulated interplay of cGMP formation and cGMP degradation. Recently, we showed that within the NO-induced cGMP response in human platelets, activation and phosphorylation of phosphodiesterase type 5 (PDE5) occurred....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173359/ https://ncbi.nlm.nih.gov/pubmed/12604588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200211041 |
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