HDAC11 suppresses the thermogenic program of adipose tissue via BRD2

Little is known about the biological function of histone deacetylase 11 (HDAC11), which is the lone class IV HDAC. Here, we demonstrate that deletion of HDAC11 in mice stimulates brown adipose tissue (BAT) formation and beiging of white adipose tissue (WAT). Consequently, HDAC11-deficient mice exhib...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Bagchi, Rushita A., Ferguson, Bradley S., Stratton, Matthew S., Hu, Tianjing, Cavasin, Maria A., Sun, Lei, Lin, Ying-Hsi, Liu, Dianxin, Londono, Pilar, Song, Kunhua, Pino, Maria F., Sparks, Lauren M., Smith, Steven R., Scherer, Philipp E., Collins, Sheila, Seto, Edward, McKinsey, Timothy A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129125/
https://ncbi.nlm.nih.gov/pubmed/30089714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120159
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