SGLT2 inhibitor dapagliflozin limits podocyte damage in proteinuric nondiabetic nephropathy

Sodium-glucose cotransporter 2 (SGLT2) inhibitors have pleiotropic properties beyond blood glucose–lowering effects and modify important nonglycemic pathways, leading to end-organ protection. SGLT2 inhibitors display renoprotective effects in diabetic kidney disease, which creates a rationale for te...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:JCI Insight
Autori principali: Cassis, Paola, Locatelli, Monica, Cerullo, Domenico, Corna, Daniela, Buelli, Simona, Zanchi, Cristina, Villa, Sebastian, Morigi, Marina, Remuzzi, Giuseppe, Benigni, Ariela, Zoja, Carlamaria
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2018
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129124/
https://ncbi.nlm.nih.gov/pubmed/30089717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98720
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