Shigatoxin-Induced Endothelin-1 Expression in Cultured Podocytes Autocrinally Mediates Actin Remodeling

Shigatoxin (Stx) is the offending agent of post-diarrheal hemolytic uremic syndrome, characterized by glomerular ischemic changes preceding microvascular thrombosis. Because podocytes are highly sensitive to Stx cytotoxicity and represent a source of vasoactive molecules, we studied whether Stx-2 mo...

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Detalhes bibliográficos
Main Authors: Morigi, Marina, Buelli, Simona, Zanchi, Cristina, Longaretti, Lorena, Macconi, Daniela, Benigni, Ariela, Moioli, Daniela, Remuzzi, Giuseppe, Zoja, Carla
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762486/
https://ncbi.nlm.nih.gov/pubmed/17148661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051331
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