In Response to Protein Load Podocytes Reorganize Cytoskeleton and Modulate Endothelin-1 Gene : Implication for Permselective Dysfunction of Chronic Nephropathies

Effacement of podocyte foot processes occurs in many proteinuric nephropathies and is accompanied by rearrangement of the actin cytoskeleton. Here, we studied whether protein overload affects intracellular pathways, leading to cytoskeletal architecture changes and ultimately to podocyte dysfunction....

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Bibliographische Detailangaben
Hauptverfasser: Morigi, Marina, Buelli, Simona, Angioletti, Stefania, Zanchi, Cristina, Longaretti, Lorena, Zoja, Carla, Galbusera, Miriam, Gastoldi, Sara, Mundel, Peter, Remuzzi, Giuseppe, Benigni, Ariela
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2005
Schlagworte:
Original Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606387/
https://ncbi.nlm.nih.gov/pubmed/15855633
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