In Response to Protein Load Podocytes Reorganize Cytoskeleton and Modulate Endothelin-1 Gene : Implication for Permselective Dysfunction of Chronic Nephropathies

Effacement of podocyte foot processes occurs in many proteinuric nephropathies and is accompanied by rearrangement of the actin cytoskeleton. Here, we studied whether protein overload affects intracellular pathways, leading to cytoskeletal architecture changes and ultimately to podocyte dysfunction....

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Main Authors: Morigi, Marina, Buelli, Simona, Angioletti, Stefania, Zanchi, Cristina, Longaretti, Lorena, Zoja, Carla, Galbusera, Miriam, Gastoldi, Sara, Mundel, Peter, Remuzzi, Giuseppe, Benigni, Ariela
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2005
Teme:
Original Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606387/
https://ncbi.nlm.nih.gov/pubmed/15855633
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