Sirtuin3 Dysfunction Is the Key Determinant of Skeletal Muscle Insulin Resistance by Angiotensin II

BACKGROUND: Angiotensin II promotes insulin resistance. The mechanism underlying this abnormality, however, is still poorly defined. In a different setting, skeletal muscle metabolism and insulin signaling are regulated by Sirtuin3. OBJECTIVE: Here, we investigate whether angiotensin II-induced insu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Macconi, Daniela, Perico, Luca, Longaretti, Lorena, Morigi, Marina, Cassis, Paola, Buelli, Simona, Perico, Norberto, Remuzzi, Giuseppe, Benigni, Ariela
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437781/
https://ncbi.nlm.nih.gov/pubmed/25993470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127172
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