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A previously unrecognized role of C3a in proteinuric progressive nephropathy

Podocyte loss is the initial event in the development of glomerulosclerosis, the structural hallmark of progressive proteinuric nephropathies. Understanding mechanisms underlying glomerular injury is the key challenge for identifying novel therapeutic targets. In mice with protein-overload induced b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Morigi, Marina, Locatelli, Monica, Rota, Cinzia, Buelli, Simona, Corna, Daniela, Rizzo, Paola, Abbate, Mauro, Conti, Debora, Perico, Luca, Longaretti, Lorena, Benigni, Ariela, Zoja, Carlamaria, Remuzzi, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921969/
https://ncbi.nlm.nih.gov/pubmed/27345360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28445
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