A previously unrecognized role of C3a in proteinuric progressive nephropathy

Podocyte loss is the initial event in the development of glomerulosclerosis, the structural hallmark of progressive proteinuric nephropathies. Understanding mechanisms underlying glomerular injury is the key challenge for identifying novel therapeutic targets. In mice with protein-overload induced b...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Morigi, Marina, Locatelli, Monica, Rota, Cinzia, Buelli, Simona, Corna, Daniela, Rizzo, Paola, Abbate, Mauro, Conti, Debora, Perico, Luca, Longaretti, Lorena, Benigni, Ariela, Zoja, Carlamaria, Remuzzi, Giuseppe
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921969/
https://ncbi.nlm.nih.gov/pubmed/27345360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28445
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