A previously unrecognized role of C3a in proteinuric progressive nephropathy

Podocyte loss is the initial event in the development of glomerulosclerosis, the structural hallmark of progressive proteinuric nephropathies. Understanding mechanisms underlying glomerular injury is the key challenge for identifying novel therapeutic targets. In mice with protein-overload induced b...

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Publicat a:Sci Rep
Autors principals: Morigi, Marina, Locatelli, Monica, Rota, Cinzia, Buelli, Simona, Corna, Daniela, Rizzo, Paola, Abbate, Mauro, Conti, Debora, Perico, Luca, Longaretti, Lorena, Benigni, Ariela, Zoja, Carlamaria, Remuzzi, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921969/
https://ncbi.nlm.nih.gov/pubmed/27345360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28445
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