Enhancing IgG distribution to lung mucosal tissue improves protective effect of anti–Pseudomonas aeruginosa antibodies

IgG antibodies are abundantly present in the vasculature but to a much lesser extent in mucosal tissues. This contrasts with antibodies of the IgA and IgM isotype that are present at high concentration in mucosal secretions due to active delivery by the polymeric Ig receptor (pIgR). IgG is the prefe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Borrok, M. Jack, DiGiandomenico, Antonio, Beyaz, Nurten, Marchetti, Gabriela M., Barnes, Arnita S., Lekstrom, Kristen J., Phipps, Sandrina S., McCarthy, Michael P., Wu, Herren, Dall’Acqua, William F., Tsui, Ping, Gupta, Ruchi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124411/
https://ncbi.nlm.nih.gov/pubmed/29925682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97844
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados