FGFR1 underlies obesity-associated progression of estrogen receptor–positive breast cancer after estrogen deprivation

Obesity increases breast cancer mortality by promoting resistance to therapy. Here, we identified regulatory pathways in estrogen receptor–positive (ER-positive) tumors that were shared between patients with obesity and those with resistance to neoadjuvant aromatase inhibition. Among these was fibro...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Wellberg, Elizabeth A., Kabos, Peter, Gillen, Austin E., Jacobsen, Britta M., Brechbuhl, Heather M., Johnson, Stevi J., Rudolph, Michael C., Edgerton, Susan M., Thor, Ann D., Anderson, Steven M., Elias, Anthony, Zhou, Xi Kathy, Iyengar, Neil M., Morrow, Monica, Falcone, Domenick J., El-Hely, Omar, Dannenberg, Andrew J., Sartorius, Carol A., MacLean, Paul S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124402/
https://ncbi.nlm.nih.gov/pubmed/30046001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120594
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