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Breast cancer suppression by progesterone receptors is mediated by their modulation of estrogen receptors and RNA polymerase III

Greater than 50% of estrogen receptor (ER)-positive breast cancers co-express the progesterone receptor (PR), which can directly and globally modify ER action to attenuate tumor growth. However, whether this attenuation is mediated only through PR-ER interaction remains unknown. To address this ques...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Finlay-Schultz, Jessica, Gillen, Austin E., Brechbuhl, Heather M., Ivie, Joshua J., Matthews, Shawna B., Jacobsen, Britta M., Bentley, David L., Kabos, Peter, Sartorius, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600857/
https://ncbi.nlm.nih.gov/pubmed/28729413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-3541
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