SCF(FBW7)-mediated degradation of Brg1 suppresses gastric cancer metastasis

Brg1/SMARCA4 serves as the ATPase and the helicase catalytic subunit for the multi-component SWI/SNF chromatin remodeling complex, which plays a pivotal role in governing chromatin structure and gene transcription. However, the upstream signaling pathways regulating Brg1 protein stability and its ph...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Huang, Li-Yu, Zhao, Junjie, Chen, Hao, Wan, Lixin, Inuzuka, Hiroyuki, Guo, Jianping, Fu, Xuhong, Zhai, Yangyang, Lu, Zhaoning, Wang, Xuefei, Han, Ze-Guang, Sun, Yihong, Wei, Wenyi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120942/
https://ncbi.nlm.nih.gov/pubmed/30177679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06038-y
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