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Elevation of the TP53 isoform Δ133p53β in glioblastomas: an alternative to mutant p53 in promoting tumor development

As tumor protein 53 (p53) isoforms have tumor‐promoting, migration, and inflammatory properties, this study investigated whether p53 isoforms contributed to glioblastoma progression. The expression levels of full‐length TP53α (TAp53α) and six TP53 isoforms were quantitated by RT‐qPCR in 89 glioblast...

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Bibliografski detalji
Izdano u:J Pathol
Glavni autori: Kazantseva, Marina, Eiholzer, Ramona A, Mehta, Sunali, Taha, Ahmad, Bowie, Sara, Roth, Imogen, Zhou, Jean, Joruiz, Sebastien M, Royds, Janice A, Hung, Noelyn A, Slatter, Tania L, Braithwaite, Antony W
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120556/
https://ncbi.nlm.nih.gov/pubmed/29888503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5111
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