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Chemical Genetic Screens Identify Kinase Inhibitor Combinations that Target Anti-Apoptotic Proteins for Cancer Therapy
The study presented here provides a framework for the discovery of unique inhibitor combinations that target the apoptosis network for cancer therapy. A pair of doxycycline (Dox) -inducible cell lines that specifically report on the ability of an inhibitor to induce apoptosis either by targeting the...
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| Pubblicato in: | ACS Chem Biol |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6119178/ https://ncbi.nlm.nih.gov/pubmed/29608269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00077 |
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