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Symbiotic Prodrugs (SymProDs) Dual Targeting of NFkappaB and CDK

The release of an active drug from the prodrug generates a pro-fragment that typically has no biological activity and could result in adverse effects. By combining two drugs wherein each drug acts as a pro-fragment of the other drug will eliminate the pro-fragment in the prodrug. Since they are prod...

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Detalhes bibliográficos
Publicado no:Chem Biol Drug Des
Main Authors: Rana, Sandeep, Kour, Smit, Sonawane, Yogesh A., Robb, Caroline M., Contreras, Jacob I., Kizhake, Smitha, Zahid, Muhammad, Karpf, Adam R., Natarajan, Amarnath
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8022330/
https://ncbi.nlm.nih.gov/pubmed/32237047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.13684
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