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A role for trypanosomatid aldo-keto reductases in methylglyoxal, prostaglandin and isoprostane metabolism

Trypanosomatid parasites are the infectious agents causing Chagas disease, visceral and cutaneous leishmaniasis and human African trypanosomiasis. Recent work of others has implicated an aldo-keto reductase (AKR) in the susceptibility and resistance of Trypanosoma cruzi to benznidazole, a drug used...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Roberts, Adam J., Dunne, Joanne, Scullion, Paul, Norval, Suzanne, Fairlamb, Alan H.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117947/
https://ncbi.nlm.nih.gov/pubmed/30045874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20180232
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