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Aldo-Keto Reductases 1B in Endocrinology and Metabolism

The aldose reductase (AR; human AKR1B1/mouse Akr1b3) has been the focus of many research because of its role in diabetic complications. The starting point of these alterations is the massive entry of glucose in polyol pathway where it is converted into sorbitol by this enzyme. However, the issue of...

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Detalhes bibliográficos
Main Authors: Pastel, Emilie, Pointud, Jean-Christophe, Volat, Fanny, Martinez, Antoine, Lefrançois-Martinez, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410611/
https://ncbi.nlm.nih.gov/pubmed/22876234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00148
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