Depressed Levels of Prostaglandin F(2α) in Mice Lacking Akr1b7 Increase Basal Adiposity and Predispose to Diet-Induced Obesity

Negative regulators of white adipose tissue (WAT) expansion are poorly documented in vivo. Prostaglandin F(2α) (PGF(2α)) is a potent antiadipogenic factor in cultured preadipocytes, but evidence for its involvement in physiological context is lacking. We previously reported that Akr1b7, an aldo-keto...

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Bibliographische Detailangaben
Hauptverfasser: Volat, Fanny E., Pointud, Jean-Christophe, Pastel, Emilie, Morio, Béatrice, Sion, Benoit, Hamard, Ghislaine, Guichardant, Michel, Colas, Romain, Lefrançois-Martinez, Anne-Marie, Martinez, Antoine
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2012
Schlagworte:
Obesity Studies
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478517/
https://ncbi.nlm.nih.gov/pubmed/22851578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1297
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