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Aldo-Keto Reductases 1B in Endocrinology and Metabolism

The aldose reductase (AR; human AKR1B1/mouse Akr1b3) has been the focus of many research because of its role in diabetic complications. The starting point of these alterations is the massive entry of glucose in polyol pathway where it is converted into sorbitol by this enzyme. However, the issue of...

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Autors principals: Pastel, Emilie, Pointud, Jean-Christophe, Volat, Fanny, Martinez, Antoine, Lefrançois-Martinez, Anne-Marie
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410611/
https://ncbi.nlm.nih.gov/pubmed/22876234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00148
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